Detroit Lions at Buffalo Bills
NFL 2026 · Week 2 · · Highmark Stadium
Detroit Lions at Buffalo Bills, Week 2 of the 2026 season: Buffalo Bills won 41–31.
Result
Detroit Lions 31–41 Buffalo Bills
Closing line BUF −5.5, total 54.5 (went over). Buffalo Bills covered.
What the model predicted beforehand
No model prediction was made before this game kicked off (predictions are only shown if they were made beforehand). The betting line is BUF −5.5, total 54.5.
Buffalo Bills
LWWLW
Detroit Lions
WWLLL
Form is each team’s last 5 games before this one, home and away (the season is only 17 games), oldest to newest; play-offs included.
2026 season before this game
| Bills | Lions | |
|---|---|---|
| Record | 1-0 | 1-0 |
| Points per game | 36.0 | 31.0 |
| Points allowed per game | 31.0 | 30.0 |
| Points difference | +5 | +1 |
| Against the spread (W-L-P) | 1-0 | 0-1 |
Head-to-head record
Buffalo Bills lead 6–1 in 7 meetings since 2002. Buffalo Bills have won the last 5.
| P | Bills | T | Lions | |
|---|---|---|---|---|
| All meetings | 7 | 6 | 0 | 1 |
| At Buffalo Bills | 3 | 3 | 0 | 0 |
- Biggest Buffalo Bills win
- Detroit Lions 17–24 Buffalo Bills (2002 Week 8)
- Biggest Detroit Lions win
- Buffalo Bills 17–20 Detroit Lions (2006 Week 6)
- Average points per meeting
- 43.6
- Buffalo Bills against the spread (W-L-P)
- 3-4
Head-to-head (last 7)
- Buffalo Bills 48–42 Detroit Lions2024 Week 15 · line DET −2.5 (Bills covered)
- Buffalo Bills 28–25 Detroit Lions2022 Week 12 · line BUF −10 (Bills did not cover)
- Detroit Lions 13–14 Buffalo Bills2018 Week 15 · line BUF −2.5 (Bills did not cover)
- Buffalo Bills 17–14 Detroit Lions2014 Week 5 · line DET −4.5 (Bills covered)
- Detroit Lions 12–14 Buffalo Bills2010 Week 10 · line BUF −1.5 (Bills covered)
- Buffalo Bills 17–20 Detroit Lions2006 Week 6 · line BUF −1 (Bills did not cover)
- Detroit Lions 17–24 Buffalo Bills2002 Week 8 · line BUF −7.5 (Bills did not cover)
Recent games
Buffalo Bills
- W@ Houston TexansWeek 1 · covered BUF −1.536–31
- L@ Denver Broncos2025 Divisional round · did not cover DEN −1.530–33 (OT)
- W@ Jacksonville Jaguars2025 Wild card round · covered JAX −1.527–24
- Wv New York Jets2025 Week 18 · covered BUF −12.535–8
- Lv Philadelphia Eagles2025 Week 17 · did not cover BUF −312–13
- W@ Cleveland Browns2025 Week 16 · did not cover BUF −10.523–20
- W@ New England Patriots2025 Week 15 · covered BUF −2.535–31
- Wv Cincinnati Bengals2025 Week 14 · did not cover BUF −639–34
- W@ Pittsburgh Steelers2025 Week 13 · covered BUF −326–7
- L@ Houston Texans2025 Week 12 · did not cover BUF −5.519–23
Recent games
Detroit Lions
- Wv New Orleans SaintsWeek 1 · did not cover DET −731–30 (OT)
- W@ Chicago Bears2025 Week 18 · covered CHI −3.519–16
- L@ Minnesota Vikings2025 Week 17 · did not cover DET −710–23
- Lv Pittsburgh Steelers2025 Week 16 · did not cover DET −7.524–29
- L@ Los Angeles Rams2025 Week 15 · did not cover LA −5.534–41
- Wv Dallas Cowboys2025 Week 14 · covered DET −3.544–30
- Lv Green Bay Packers2025 Week 13 · did not cover DET −2.524–31
- Wv New York Giants2025 Week 12 · did not cover DET −1434–27 (OT)
- L@ Philadelphia Eagles2025 Week 11 · did not cover PHI −2.59–16
- W@ Washington Commanders2025 Week 10 · covered DET −8.544–22